MYELOID NEOPLASIA High VEGFC expression is associated with unique gene expression profiles and predicts adverse prognosis in pediatric and adult acute myeloid leukemia
نویسندگان
چکیده
1Division of Pediatric Oncology/Hematology, Department of Pediatrics, Beatrix Children’s Hospital, University Medical Center Groningen, University of Groningen, Groningen; 2Department of Hematology, Erasmus University Medical Center, Rotterdam; 3Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen; 4Department of Pediatric Oncology/Hematology, Erasmus MC–Sophia Children’s Hospital, Rotterdam; 5Division of Pediatric Oncology/Hematology, VU University Medical Center, Amsterdam; and 6Dutch Childhood Oncology Group, The Hague, The Netherlands
منابع مشابه
High VEGFC expression is associated with unique gene expression profiles and predicts adverse prognosis in pediatric and adult acute myeloid leukemia.
High VEGFC mRNA expression of acute myeloid leukemia (AML) blasts is related to increased in vitro and in vivo drug resistance. Prognostic significance of VEGFC on long-term outcome and its associated gene expression profiles remain to be defined. We studied effect of VEGFC on treatment outcome and investigated gene expression profiles associated with VEGFC using microarray data of 525 adult an...
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